Best Biohacking Supplements for Weight Loss For Women Over 40

Losing weight after 40 can feel like an uphill battle. Your metabolism slows, hormones shift, and what used to work no longer delivers the same results. But don’t worry—I’ve got you! If you’ve been struggling to shed those stubborn pounds, biohacking may be the game-changer you need.

This is one of my all time favorite biohacking supplements for weight loss for women over 40.  It has made a huge difference for me—check it out here!

Biohacking is all about using science-backed strategies to optimize your body’s natural fat-burning abilities. With the right supplements, you can enhance your metabolism, balance hormones, and make weight loss easier than ever. So, let’s dive into the best biohacking supplements for women’s weight loss over 40 who want to burn fat and feel amazing.

1. Berberine – The Metabolism Booster

Berberine has been a staple in traditional Chinese medicine for centuries, but it’s making waves in the biohacking world for its metabolism-boosting properties.

Why it’s great for women over 40:

  • Improves insulin sensitivity (key for stubborn fat loss)
  • Activates AMPK (the “metabolic master switch”)
  • Helps regulate blood sugar levels
  • Supports gut health, which plays a role in weight management

💡 How to Use: Start with 500mg per day and gradually increase to 1500mg, taken in divided doses with meals.

🔎 Potential Side Effects: Some digestive discomfort is possible when starting. If this happens, ease into it slowly.

Check out a top-rated berberine supplement here!

2. Exogenous Ketones – The Fat Burner

If you’ve ever considered keto but hate the idea of giving up carbs entirely, exogenous ketones might be the perfect hack for you. They help your body enter ketosis faster, so you burn fat for fuel more efficiently.

Why it’s great for women over 40:

  • Helps curb cravings and reduce appetite
  • Increases mental clarity and focus
  • Boosts energy levels without the crash

💡 How to Use: Take before a workout or while fasting for maximum fat-burning benefits.

🔎 Potential Side Effects: Some people experience digestive discomfort or electrolyte imbalances. Stay hydrated and consider adding electrolytes.

Find the best exogenous ketones here!

3. Green Tea Extract – The Metabolism Igniter

Green tea extract is loaded with EGCG, a powerful antioxidant that enhances metabolism and fat oxidation.

Why it’s great for women over 40:

  • Boosts metabolism naturally
  • Enhances fat burning (especially during exercise)
  • Provides a steady energy boost without jitters
  • Supports overall health with antioxidants

💡 How to Use: Look for a supplement with at least 50% EGCG. Take 250-500mg per day before meals.

🔎 Potential Side Effects: Can cause nausea or liver issues in high doses. Stick to recommended amounts.

Get a top-quality green tea extract here!

4. Rhodiola Rosea – The Stress Buster

Hormonal changes and increased stress can make weight loss harder. Rhodiola is an adaptogen that helps your body handle stress better, keeping cortisol levels in check.

Why it’s great for women over 40:

  • Lowers cortisol (which can lead to belly fat storage)
  • Increases energy and fights fatigue
  • Supports mental clarity and mood

💡 How to Use: Take 200-600mg in the morning to set yourself up for a stress-free day.

🔎 Potential Side Effects: May cause mild dizziness or dry mouth in some users.

Check out a highly-rated Rhodiola supplement here!

5. Probiotics – The Gut Healer

Your gut health plays a massive role in weight management. Certain probiotic strains can help reduce inflammation, improve digestion, and even influence fat storage.

Why it’s great for women over 40:

  • Helps regulate appetite and reduce cravings
  • Supports digestion and nutrient absorption
  • Reduces inflammation linked to stubborn weight gain

💡 How to Use: Look for a multi-strain probiotic with Lactobacillus gasseri, which has been shown to reduce belly fat.

🔎 Potential Side Effects: Some mild bloating or digestive discomfort when starting out.

Find the best probiotic for weight loss here!

How to Get the Most Out of Your Biohacking Supplements

To maximize your results, follow these simple strategies:

Start Slow: Introduce one supplement at a time to see how your body reacts. ✅ Track Your Progress: Keep a journal of your energy levels, weight, and overall well-being. ✅ Combine with Lifestyle Changes: Supplements work best alongside a healthy diet and exercise routine. ✅ Cycle Your Supplements: To avoid adaptation, consider taking breaks from certain supplements every few months.

Bonus: Biohacking Habits for Even Faster Results

  • Intermittent Fasting: Pair with your supplements for enhanced fat-burning.
  • Strength Training: Helps maintain muscle mass and boost metabolism.
  • Cold Exposure: A quick cold shower can activate brown fat and increase calorie burn.
  • Mindful Eating: Tune into your hunger cues to prevent overeating.

Final Thoughts

Losing weight over 40 doesn’t have to be a struggle. With the best biohacking supplements for women’s weight loss over 40 and a few lifestyle tweaks, you can optimize your metabolism, balance hormones, and finally shed those stubborn pounds.

Start with one or two supplements that fit your needs, and remember—consistency is key!

🚀 Ready to start your biohacking journey? Check out the best biohacking supplements for women’s weight loss over 40 and take the first step toward feeling your absolute best! Browse top picks here.